Behind the Label: What CGMP Certification Really Means for quality supplements

Why Supplement Quality Matters

In a growing wellness industry filled with options, quality supplements have never been more important—or more misunderstood. From raw ingredient sourcing to final packaging, every step in production affects safety, potency, and effectiveness.

That’s where CGMP certification comes in. Standing for Current Good Manufacturing Practices, CGMP standards are the backbone of supplement quality control in the United States. They ensure every capsule you take has been produced in a facility that meets the highest federal guidelines for consistency, cleanliness, and reliability.

At Priority One Vitamins, these standards are not just boxes to check—they’re the foundation of how we operate. Every product is made in our own NSF-certified CGMP facility in the Pacific Northwest, combining rigorous testing, precision formulation, and decades of clinical expertise.

What CGMP Certification Really Means

The term “CGMP” comes from the FDA’s quality framework for dietary supplements, ensuring that each product is manufactured under controlled conditions. It governs everything from:

• Ingredient sourcing and verification

• Equipment calibration and cleanliness

• Staff training and safety procedures

• In-process testing and recordkeeping

• Label accuracy and finished-product testing

When a facility is CGMP certified, it means that every process—from raw material receipt to final bottling—is documented, validated, and inspected for compliance helping ensure quality supplements.

For consumers, this certification provides confidence that the quality supplements they’re taking contain exactly what the label claims—and nothing more.

Why It Matters to You

Not all supplement companies are CGMP certified, and even fewer maintain in-house production and testing. Many brands outsource manufacturing to third-party facilities, often with limited oversight of the supply chain.

Priority One Vitamins is different. We control every phase of the process, which allows us to:

• Verify ingredient identity and purity before production begins.*

• Monitor potency and consistency throughout manufacturing.*

• Perform full microbial and contaminant testing on every batch.*

• Ensure label accuracy by validating formulations from start to finish.*

This meticulous attention to detail helps protect your health and guarantees that each product performs as intended.

Priority One’s Manufacturing Difference: Verified at Every Step

At Priority One Vitamins, our commitment to making quality supplements extends far beyond basic compliance—it’s woven into every stage of production. Our state-of-the-art manufacturing facility is both NSF-certified and fully CGMP compliant, ensuring transparency, safety, and precision in every product we produce.

NSF Certification: Exceeding Industry Standards

While CGMP certification represents the FDA’s gold standard for dietary supplement manufacturing, NSF International certification goes even further. NSF audits evaluate facilities for adherence to higher-level safety, documentation, and process standards—providing additional third-party assurance that each step of production meets or surpasses federal requirements.

Priority One Vitamins has earned an “A” rating from NSF for compliance with these rigorous standards, reflecting our ongoing dedication to manufacturing excellence of quality supplements. NSF certification is not a one-time event; it involves continuous auditing, testing, and validation to ensure that procedures remain at the highest level of consistency and control.

Equally important, Priority One Vitamins has maintained a clean FDA inspection record for over a decade, with no comments or observations of concern—a rare distinction that underscores our unwavering commitment to safety and quality.

Our In-House Laboratory: Science at the Core of Every Capsule

Unlike many brands that rely solely on external verification, Priority One maintains a fully equipped analytical laboratory within our manufacturing facility. This allows us to perform comprehensive in-house lab testing to verify, monitor, and control the quality of every ingredient and finished product in real time.

Our lab utilizes advanced analytical technologies, including:

• HPLC (High-Performance Liquid Chromatography): Used to verify botanical identity, active compound concentration, and potency.*

• ICP-MS (Inductively Coupled Plasma Mass Spectrometry): Detects and quantifies heavy metals and mineral content with exceptional accuracy and sensitivity.*

• Soleris Microbial Testing System: Rapidly screens for E. coli, Salmonella, yeast, mold, and a full range of microbial contaminants.*

This combination of technologies allows us to conduct testing throughout the entire production process—from raw material verification to final encapsulation—rather than relying solely on end-batch testing.

While our in-house laboratory provides unmatched control, precision, and speed, we also partner with ISO-certified third-party laboratories for independent verification. This dual-testing approach ensures every product is third-party tested, providing unbiased results, total transparency, and adherence to the most rigorous NSF and CGMP standards in the supplement industry.

By maintaining such a comprehensive analytical framework, Priority One Vitamins ensures that each product consistently meets or exceeds expectations for purity, potency, and safety—delivering the professional-grade integrity practitioners and consumers can trust.*

Beyond CGMP: What Sets Priority One Apart

CGMP certification is only the beginning. Our quality philosophy includes additional measures that define us as a true practitioner-grade supplement brand:

• Clinical Formulation Expertise: Every formula is designed by healthcare professionals with extensive experience in functional and integrative medicine.*

• Premium Ingredient Sourcing: We work exclusively with trusted global suppliers, verifying identity and quality at multiple checkpoints.*

• Glandular Integrity: For glandular formulas, we use freeze-dried tissue from grass-fed, finished New Zealand cattle, ensuring optimal structure and bioavailability.*

• Transparency: All labels clearly state active ingredients, excipients, and allergens—so you know exactly what you’re taking.

• Sustainability and Stewardship: Our facility operates within an environmentally conscious business park in the Pacific Northwest, reflecting our long-standing commitment to ethical manufacturing.

Every element—from the raw materials to the final label—reflects our belief that quality is not an act; it’s a standard.

Reading the Label: What Practitioners—and Informed Consumers—Look For

Professional practitioners evaluate quality supplements through a clinical lens, focusing on formulation precision, evidence-based ingredient selection, and manufacturing transparency. But today’s health-conscious consumers are increasingly asking the same questions—seeking the same professional-grade standards trusted in clinical practice.

At Priority One Vitamins, we design every formula to meet the expectations of both groups: healthcare practitioners who demand therapeutic consistency, and everyday consumers who value safety, purity, and proven quality supplements.

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Here’s what sets our labels—and our products—apart:

• Dosage Accuracy: Each product delivers consistent potency that aligns with clinical use and therapeutic intent.*

• Transparency: Every label clearly lists active ingredients, excipients, capsule materials, and allergen disclosures—no hidden blends or surprises.*

• Testing Certifications: Our products are both NSF certified and CGMP compliant, and undergo rigorous in-house and third-party testing to confirm purity, potency, and identity.*

• Manufacturing Integrity: Every capsule is produced in our NSF “A”-rated facility, with a decade-long record of FDA compliance and zero areas of concern.

• Accessible Professional Quality: While trusted and prescribed by practitioners nationwide, Priority One formulas are also available directly to individuals who want to take a professional-grade approach to their wellness.

Whether you’re a clinician recommending products in practice or a consumer choosing supplements for your own health, Priority One Vitamins provides the same uncompromising quality, safety, and consistency—verified at every step.*

Transparency in Action: Product Spotlight and COA Verification

At Priority One Vitamins, quality isn’t just a promise—it’s something we prove. Every product we manufacture undergoes comprehensive testing to verify purity, potency, and identity, and we make those results available through our Certificate of Analysis (COA) system.

Each COA details the batch-specific testing results for the product, confirming that it meets all internal and third-party specifications for:

• Identity and Potency: Verified through HPLC and ICP-MS analysis.*

• Microbial Purity: Tested using Soleris microbial detection for E. coli, Salmonella, yeast, and mold.*

• Heavy Metals and Minerals: Screened to ensure compliance with stringent safety thresholds.*

For example, below you can see our product Hormone Clear and the accompanying COA for the most recently made batch which  showcases this commitment to transparency. Every batch is tested on-site in our NSF-certified laboratory and verified by accredited third-party partners before release.

Providing a COA for each production batch allows practitioners and consumers alike to verify the quality and consistency of what’s inside every bottle—offering confidence that each formula performs exactly as intended and that they are getting quality supplements.*

Hormone Clear™ (90 cápsulas vegetarianas) es una fórmula integral que apunta al equilibrio hormonal.*

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Hormone Clear™ es una formulación exclusiva de la Dra. Marianne Marchese, autora del libro más vendido, 8 Weeks to Women's Wellness. . Hormone Clear, un suplemento para el equilibrio hormonal, es una combinación única de aminoácidos, antioxidantes y nutrientes que… read more

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Transparency is the foundation of trust—and at Priority One Vitamins, we believe you deserve to see the proof.

The Doctor-Formulated Difference

At Priority One Vitamins, every formulation begins with science, integrity, and decades of clinical insight. Our team works directly with leading healthcare professionals who bring real-world experience into every product we produce helping us make quality supplements. Each of these practitioners has contributed their unique expertise to help shape our professional-grade supplement line—grounded in evidence, built for results, and trusted by clinicians nationwide.*

Dr. Mona Morstein, ND — Expert in Digestive and Endocrine Health

Dr. Mona Morstein is a nationally recognized naturopathic physician and founder of Arizona Integrative Medical Solutions. With over 35 years of clinical practice, she is one of the foremost authorities on gastrointestinal and metabolic conditions, including SIBO (Small Intestinal Bacterial Overgrowth). Her clinical insight led to the creation of the Priority One SIBO Protocol, a structured, phase-based system supporting microbial balance, intestinal motility, and gut restoration.*

Dr. Paul S. Anderson, ND — Innovator in Advanced Nutritional Medicine

Dr. Paul Anderson is a pioneer in integrative medicine and clinical research, known for his expertise in complex chronic conditions and biofilm disruption strategies. As the formulator of Biofilm Phase-2 Advanced, Dr. Anderson developed a professional-strength blend designed to support the body’s natural ability to address resilient microbial communities and maintain intestinal balance.* His extensive teaching, authorship, and clinical training have helped define modern naturopathic approaches to advanced gastrointestinal support.*

Dr. Jennifer Marchese, ND — Leader in Women’s Health and Hormonal Balance

Dr. Jennifer Marchese brings decades of experience in women’s health, hormonal regulation, and stress adaptation. Her work focuses on integrative solutions that support endocrine harmony through targeted nutrition and glandular therapy. As one of Priority One’s long-standing collaborators, she has contributed to formulations like Hormone clear designed to promote adrenal balance, thyroid integrity, and overall vitality.*

Together, these practitioners represent the foundation of Priority One Vitamins’ doctor-formulated excellence—combining medical knowledge, research, and clinical practice with our in-house manufacturing precision. Every bottle reflects a partnership between scientific craftsmanship and real-world patient care, ensuring that each product meets the highest standard of professional trust and therapeutic reliability.*

FDA Disclaimer

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.