Had Lethargy, low energy, thinking problems, every day. That got MUCH worse as the day progressed. Napped every day after lunch. NOW I RARELY need a nap in the afternoon. And frequently can-do chores/hobbies etc. in the evening after dinner. I used to do nothing but watch TV in the evening because of impaired thinking, lethargy/tiredness/fatigue. My slow thinking has improved some too! I take the 32.5 mg once and occasionally twice a day, morning & dinner time. Have been taking it for 3 weeks. But noticed improvement on day 1.