Hemo-X™ — Quatrefolic® Active Folate, Ultra-High Methylcobalamin B12, Ferrous Gluconate Iron & Haematopoietic Glandular Support for Normal Red Blood Cell Formation
Hemo-X™ is a precision haematopoietic support formula that addresses all three primary nutritional requirements for normal red blood cell formation — folate, B12, and iron — each in its most bioavailable or well-tolerated form, alongside glandular concentrates that support the physiological environment for normal iron absorption and red blood cell production.*
Please note: Hemo-X™ is encapsulated in gelatin — not suitable for vegetarians or vegans.
Serving size is 1 capsule, 120 servings per container.
What's inside and why it matters
Vitamin C as Ascorbic Acid (200mg, 222% DV) — At 200mg per capsule, Vitamin C plays a critical role beyond general antioxidant support. Ascorbic acid directly enhances non-haem iron absorption by reducing ferric iron (Fe³⁺) to the more readily absorbed ferrous form (Fe²⁺) in the intestinal lumen — a mechanism that can significantly increase iron bioavailability. Inclusion of Vitamin C alongside ferrous gluconate is a clinically validated strategy for maximising iron absorption.*
Thiamine HCl (Vitamin B1, 5mg, 417% DV) — Supporting normal energy metabolism in rapidly dividing erythroid progenitor cells (the precursor cells that give rise to red blood cells in the bone marrow).*
Vitamin B6 as Pyridoxine HCl (5mg, 294% DV) — A critical cofactor for haem synthesis. Pyridoxal 5-phosphate (the active B6 form) is an essential cofactor for delta-aminolevulinate synthase (ALAS) — the rate-limiting enzyme in the haem biosynthesis pathway. Without adequate B6, haem synthesis is impaired regardless of iron availability.*
Folate as Quatrefolic® (6S)-5-Methyltetrahydrofolic acid glucosamine salt (1,359mcg DFE / 1,480mcg folate equivalent, 340% DV) — Quatrefolic® is a patented, registered trademark active folate from Gnosis S.p.A. (US Patent 7,947,662), delivering L-methylfolate as the choline salt — the most bioavailable and stable form of active folate, bypassing the MTHFR enzyme entirely.*
Folate is one of the two most critical nutrients for normal red blood cell formation. Rapidly dividing erythroid progenitor cells in the bone marrow have among the highest folate requirements of any cell type — folate is essential for the thymidylate synthase reaction that synthesises the DNA bases required for cell division. At 1,359mcg DFE (340% DV), delivered as Quatrefolic® active methylfolate, this provides a meaningful, highly bioavailable folate dose regardless of MTHFR genetic status.*
Vitamin B12 as Methylcobalamin (3,004mcg, 125,167% DV) — At 3,004mcg — 125,167% of the daily value — this is a deliberately extraordinary B12 dose. Methylcobalamin is the active, neurologically ready form of B12 that operates directly in the methylation cycle.*
B12 works as an essential partner with folate at the methionine synthase reaction — without adequate B12, folate becomes trapped in a form unusable for DNA synthesis, producing the same megaloblastic anaemia picture as folate deficiency. By pairing Quatrefolic® active folate with an extremely high methylcobalamin dose, Hemo-X™ ensures both sides of this critical metabolic partnership are fully supplied.*
The very high dose also addresses the reality that B12 absorption is limited by intrinsic factor (IF) — the gastric glycoprotein required for active B12 uptake, which declines with age. At doses above ~1,000mcg, a meaningful proportion of B12 is absorbed passively via diffusion — making the high dose of 3,004mcg clinically relevant for individuals with impaired active B12 absorption.*
Iron as Ferrous Gluconate (18mg, 100% DV) — Iron at 100% of the daily value in the ferrous gluconate form — a well-tolerated, organic iron salt significantly less likely to cause the GI irritation, nausea, and constipation commonly associated with ferrous sulphate or ferrous fumarate. Iron is the central nutrient of haemoglobin synthesis — each haemoglobin molecule contains four haem groups, each with one iron atom at its core.*
Betaine HCl 98% (50mg) — Supporting normal gastric acid production for optimal iron ionisation and absorption. Iron absorption is highly pH-dependent — adequate gastric acid is required for the reduction of dietary and supplemental iron to the absorbable ferrous form.*
Stomach Glandular Concentrate (50mg) — The stomach is the primary site of gastric acid production and intrinsic factor secretion — both critical for normal iron and B12 absorption respectively. Stomach glandular concentrate provides tissue-specific factors from the gastric mucosa, supporting the normal physiological environment for iron and B12 absorption.*
Duodenum Glandular Concentrate (50mg) — The duodenum is the primary site of iron absorption — where the divalent metal transporter 1 (DMT1) actively transports ferrous iron across the intestinal epithelium. Duodenum glandular concentrate provides tissue-specific factors from the primary iron-absorbing segment of the small intestine.*
Liver Glandular Concentrate (10mg) — The liver is the central organ of iron storage (as ferritin and haemosiderin), iron recycling (via hepcidin regulation), and red blood cell production support. Liver glandular concentrate provides tissue-specific factors including naturally occurring haem iron, ferritin fractions, and hepatic regulatory proteins involved in normal iron metabolism.*
The complete haematopoietic support strategy
Hemo-X™ addresses normal red blood cell formation from four complementary angles: (1) DNA synthesis support via Quatrefolic® active folate at 340% DV; (2) methylation cycle and megaloblastic anaemia prevention via methylcobalamin B12 at 3,004mcg; (3) haem and haemoglobin synthesis support via ferrous gluconate iron at 100% DV and B6 as haem synthesis cofactor; and (4) absorption physiology support via Vitamin C, Betaine HCl, and Stomach/Duodenum/Liver glandular concentrates.*
At a glance — what this formula supports
- Normal red blood cell formation via Quatrefolic® active folate & methylcobalamin B12*
- Normal haemoglobin and haem synthesis via ferrous gluconate iron & pyridoxine B6*
- Normal iron absorption via Vitamin C, Betaine HCl & Stomach/Duodenum glandulars*
- Normal B12 absorption physiology via Stomach glandular & high passive-absorption B12 dose*
- Normal hepatic iron metabolism and storage via Liver glandular concentrate*
- Normal methylation and homocysteine clearance via Quatrefolic® & methylcobalamin*
Quality you can verify
Every batch of Hemo-X™ is manufactured in a GMP-certified facility and third-party tested for purity and potency. Features Quatrefolic® (Gnosis S.p.A., US Patent 7,947,662). Gelatin capsule — not suitable for vegetarians or vegans.
120 capsules per bottle.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Warnings
WARNING: If you are pregnant or breastfeeding, consult your physician before using this product — contains iron and active folate, both critical during pregnancy. If you have haemochromatosis, iron overload, or any blood disorder, consult your healthcare provider before use. Not suitable for vegetarians or vegans. Keep out of reach of children.
