Stress Plex™ — Optifolin+®, VitaCholine®, ChromeMate®, Ultra-High Pantothenic Acid & Adaptogenic Support for Comprehensive Stress Resilience & Adrenal Function
Stress Plex™ is a comprehensive stress and adrenal support formula combining three patented registered trademark ingredients — Optifolin+® active folate, VitaCholine®, and ChromeMate® — with an ultra-high-dose pantothenic acid B5 complex, adaptogenic botanicals, and full high-potency B vitamins. Delivered as a tablet for individuals who prefer tablet-form B complex delivery.*
Serving size is 3 tablets, 30 servings per container (90 tablets).
What's inside and why it matters
Vitamin C as Ascorbic Acid (500mg, 556% DV) — At 500mg, Vitamin C provides the adrenal support foundation — the adrenal glands have among the highest Vitamin C concentrations of any tissue and require Vitamin C for normal cortisol synthesis. Vitamin C is rapidly depleted by stress and is one of the primary nutritional interventions for adrenal support.*
Thiamine HCl (Vitamin B1, 100mg, 8,333% DV), Riboflavin (Vitamin B2, 95mg, 7,308% DV), Niacin as Niacinamide (100mg NE, 625% DV), Vitamin B6 as Pyridoxine HCl (100mg, 5,882% DV) — A high-potency, complete B vitamin complex supporting normal cellular energy metabolism, neurotransmitter synthesis, and adrenal cortex function throughout.*
Folate as Optifolin+® (6S)-5-Methyltetrahydrofolate Choline Salt (680mcg DFE, 170% DV) — Optifolin+® is a patented, registered trademark active folate from Balchem Corporation — the most bioavailable and stable form of L-methylfolate, bypassing the MTHFR enzyme entirely. Supporting normal methylation and healthy homocysteine metabolism.*
Vitamin B12 as Methylcobalamin (500mcg, 20,833% DV) — The active, neurologically ready form of B12 at a very high 500mcg dose, supporting normal methylation and neurological function.*
Biotin USP (100mcg, 333% DV) — USP-grade biotin supporting normal fatty acid synthesis and carboxylase enzyme function.*
Pantothenic Acid as d-Calcium Pantothenate (455mg, 9,100% DV) — The highest pantothenic acid dose in any Priority One formula at 9,100% of the daily value. Pantothenic acid (Vitamin B5) is the precursor to Coenzyme A (CoA) — the essential cofactor for adrenal steroid hormone synthesis including cortisol, DHEA, and aldosterone. The adrenal cortex requires CoA for the cholesterol side-chain cleavage reaction that initiates all steroid hormone synthesis. Without adequate pantothenic acid, adrenal steroid synthesis is impaired. Pantothenic acid is traditionally called the "anti-stress vitamin" specifically because of this adrenal cortisol support role.*
At 455mg — 9,100% of the daily value — Stress Plex delivers an ultra-high therapeutic pantothenic acid dose, the highest in the Priority One range.*
VitaCholine® Choline as Choline L(+) Bitartrate (45mg, 8% DV) — VitaCholine® is a patented, registered trademark choline from Balchem Corporation, supporting normal acetylcholine synthesis, healthy cell membrane integrity, and normal methylation.*
Zinc as Zinc Picolinate Chloride (16mg, 145% DV) — Zinc picolinate in a highly bioavailable form at 145% DV, supporting normal adrenal enzyme function and cortisol regulation.*
ChromeMate® Chromium as Chromium Chloride Hexahydrate Polynicotinate (200mcg, 571% DV) — ChromeMate® is a patented, registered trademark chromium complex from InterHealth Nutraceuticals at 571% DV, supporting normal glucose metabolism and healthy insulin sensitivity — both relevant to adrenal and stress response since cortisol dysregulation affects blood sugar balance.*
PABA (Para-Aminobenzoic Acid, 50mg) — Supporting normal folate utilisation and healthy B vitamin metabolism.*
Inositol (100mg) — Supporting normal cellular signalling, healthy serotonin receptor sensitivity, and normal lipid metabolism.*
Bioflavonoids Extract 25% from Bitter Orange fruit (250mg) — A citrus bioflavonoid complex supporting Vitamin C activity, healthy capillary integrity, and normal antioxidant protection.*
Licorice Root (Glycyrrhiza glabra, 500mg) — The primary adrenal support botanical in this formula. Licorice root supports normal cortisol availability through its primary mechanism of inhibiting 11-beta-HSD2 — the enzyme that converts active cortisol to inactive cortisone — supporting normal cortisol tissue availability. At 500mg, licorice root provides a substantial adrenal-supportive botanical dose.*
Please note: This is standard licorice root (not DGL) retaining its glycyrrhizin content. Regular use at 500mg may affect blood pressure — consult a healthcare provider if you have hypertension or are taking medications.
Asian Ginseng Root Extract 5% Ginsenosides (Panax ginseng, 250mg) — Standardised to 5% ginsenosides, providing 12.5mg of active ginsenosides per serving. Panax ginseng is one of the most extensively researched adaptogens for normal HPA axis modulation, normal adrenal function, and healthy energy and cognitive performance under stress.*
At a glance — what this formula supports
- Normal adrenal steroid hormone synthesis via Pantothenic Acid 455mg (9,100% DV) & Vitamin C 500mg*
- Normal cortisol tissue availability via Licorice Root 500mg*
- Adaptogenic HPA axis support via Panax Ginseng 5% ginsenosides*
- Normal methylation via Optifolin+® active folate & methylcobalamin B12 500mcg*
- Normal glucose metabolism relevant to stress response via ChromeMate® chromium*
- Normal neurotransmitter synthesis via high-potency B complex & B6 100mg*
Quality you can verify
Every batch of Stress Plex™ is manufactured in a GMP-certified facility and third-party tested for purity and potency. Features Optifolin+® and VitaCholine® (Balchem Corporation) and ChromeMate® (InterHealth Nutraceuticals) — three registered trademark branded ingredients.
90 tablets per bottle (30 servings).
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Warnings
WARNING: If you are pregnant or breastfeeding, consult your physician before using this product. This formula contains standard licorice root (glycyrrhizin-containing) at 500mg — consult your healthcare provider before use if you have hypertension, a cardiovascular condition, or are taking medications. If you have a medical condition or are taking any prescription drugs, consult your healthcare provider before use.
