Adrenoplex — Multi-Glandular & Adaptogenic Support for HPA Axis Function & Stress Resilience
The body's stress response is coordinated by the HPA axis — a communication system between the hypothalamus, pituitary gland, and adrenal glands. Adrenoplex is formulated to support all three components of this system, combining targeted multi-glandular concentrates with essential nutritional cofactors and adaptogenic botanicals in a single, comprehensive formula.*
What's inside and why it matters
Adrenal Glandular Concentrate (Bovine, grass-fed) — Whole adrenal glandular concentrate provides tissue-specific enzymes, peptides, and cofactors naturally found in the adrenal gland, supporting normal adrenal function through the principle of whole gland nutrition.*
Adrenal Cortex Concentrate (Bovine, grass-fed) — The adrenal cortex is the outer layer of the adrenal gland and the site of cortisol and other adrenal hormone production. Including adrenal cortex concentrate alongside whole adrenal glandular provides more targeted support to this specific and critical region of the gland. This dual-glandular approach is what sets Adrenoplex apart from single-glandular adrenal formulas.*
Pituitary Glandular Concentrate (Bovine, grass-fed) — The pituitary gland sits at the top of the HPA axis, signalling the adrenal glands to produce stress hormones. Including pituitary glandular concentrate supports the full axis — not just the adrenals in isolation — making this a genuinely systemic approach to HPA support.*
Vitamin C (Ascorbic Acid) — An essential cofactor in normal adrenal hormone synthesis. The adrenal glands are among the highest Vitamin C-retaining tissues in the body, and Vitamin C requirements increase significantly during periods of sustained stress.*
Pantothenic Acid (Vitamin B5) — Directly involved in the synthesis of coenzyme A and normal adrenal hormone production. Pantothenic acid is one of the most well-established nutritional cofactors for adrenal support and is included here at a meaningful dose.*
Zinc (as Zinc Orotate) — Zinc orotate is a well-absorbed form of zinc, chosen here for its superior bioavailability over oxide forms. Zinc supports normal immune function, cellular repair, and overall endocrine health — all of which can be taxed during sustained periods of stress.*
Vitamin A (as Beta-Carotene) — A precursor to Vitamin A that the body converts as needed, supporting normal immune function, cellular health, and antioxidant protection.*
Eleuthero Root Extract (Siberian Ginseng) — A widely studied adaptogenic herb that supports the body's normal ability to adapt to physical and emotional stress and contributes to healthy energy levels and stamina.*
Licorice Root Extract — Supports healthy adrenal function and normal cortisol metabolism. Licorice is a well-established botanical in adrenal support formulas for its role in supporting the body's normal HPA axis regulation.*
Why the multi-glandular approach matters
Most adrenal glandular products contain a single concentrate — usually whole adrenal or adrenal cortex alone. Adrenoplex includes both, plus pituitary glandular, to support the full HPA axis rather than one point in the chain. Combined with targeted vitamins, a highly bioavailable form of zinc, and two complementary adaptogenic botanicals, this is Priority One's most comprehensive formula for HPA axis and adrenal support.*
At a glance — what this formula supports
- Normal HPA axis function across the hypothalamus, pituitary, and adrenal glands*
- Normal adrenal hormone synthesis and healthy adrenal function*
- Sustained energy levels and reduction of occasional fatigue*
- The body's normal ability to adapt to physical and emotional stress*
- Normal immune function during periods of sustained stress*
- Healthy cortisol metabolism and adrenal hormone balance*
Quality you can verify
Every batch of Adrenoplex is sourced from grass-fed bovine glandular material, manufactured in a GMP-certified facility, and third-party tested for purity and potency. No unnecessary fillers or additives.
90 capsules per bottle.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Warnings
WARNING: If you are pregnant or breastfeeding, consult your physician before using this product. Not intended for use by individuals with known sensitivities to bovine-derived ingredients. If you have a hormone-sensitive condition or are taking medications, consult your healthcare provider before use.
