Hepa Cleanse™ — Five Standardised Botanical Extracts for Liver Detoxification, Bile Support & Hepatic Health
Hepa Cleanse™ was developed exclusively by Dr. Marchese — a naturopathic physician with a specialisation in liver health and hepatic detoxification — as a precision botanical formula for comprehensive liver support. Rather than a generic liver tonic with many ingredients at inconsequential doses, Hepa Cleanse™ delivers five well-established liver-supportive botanicals, each standardised to its primary active compounds, each at a meaningful 200mg dose per serving.*
Serving size is 2 vegetarian capsules, 30 servings per container (60 capsules).
What's inside and why it matters
Milk Thistle Seed Extract 80% Silymarin (Silybum marianum, 200mg per serving)
Milk thistle is the most extensively researched hepatoprotective botanical in the world, and silymarin — a mixture of flavonolignans found in the seed — is its primary active compound complex. At 200mg standardised to 80% silymarin, this provides 160mg of active silymarin per serving — a clinically meaningful dose that reflects the amounts used in published research on liver support.*
Silymarin supports normal liver cell membrane integrity by competing with toxins for binding sites on hepatocyte membranes, supports normal antioxidant defence in hepatic tissue (including glutathione synthesis), and supports normal liver cell regeneration through stimulation of hepatocyte protein synthesis. Milk thistle is the foundational ingredient in this formula and the most important single botanical for direct hepatoprotective support.*
Burdock Root Extract 4:1 (Arctium lappa, 200mg per serving)
A 4:1 concentrated extract equivalent to 800mg of raw burdock root per serving. Burdock has a long history of use in European and Asian traditional medicine as a liver tonic. Modern phytochemical research has identified inulin, polyacetylenes, and phenolic acids as its primary active constituents. Burdock supports normal hepatic detoxification pathways, healthy lymphatic function, and the normal elimination of metabolic waste through the liver and kidneys.*
Dandelion Root Extract 20% Taraxasterols (Taraxacum officinale, 200mg per serving)
Standardised to 20% taraxasterols — the primary bioactive terpenoids associated with dandelion's hepatic activity — this is a potency-verified, standardised extract providing 40mg of active taraxasterols per serving. Dandelion root is one of the most widely used traditional liver and bile-supportive botanicals, with a long history in European, North American, and traditional Chinese medicine for supporting normal bile production, healthy hepatic function, and normal diuretic activity.*
Taraxasterols and related triterpenoids in dandelion support normal bile flow from the liver and gallbladder, which is directly relevant to fat digestion, cholesterol metabolism, and the normal clearance of metabolic waste. Standardisation to 20% ensures consistent, meaningful taraxasterol content in every serving.*
Artichoke Leaf Extract 5% Cynarin (Cynara scolymus, 200mg per serving)
Standardised to 5% cynarin — the primary bioactive hydroxycinnamic acid responsible for artichoke's hepatic and choleretic (bile-stimulating) properties — this is a potency-verified extract providing 10mg of active cynarin per serving. Artichoke leaf has been extensively studied in European herbal medicine for its role in supporting normal hepatic function, healthy bile secretion, and normal lipid metabolism.*
Cynarin and the related chlorogenic acid derivatives in artichoke leaf support the normal production and secretion of bile from the liver, support normal antioxidant defence in hepatic tissue, and have been studied for their role in supporting healthy lipid metabolism — making artichoke leaf an important complement to the milk thistle and dandelion in this formula.*
Beet Root Extract 4:1 (Beta vulgaris, 200mg per serving)
A 4:1 concentrated extract equivalent to 800mg of raw beet root per serving. Beet root is included for its betaine (trimethylglycine) content — a direct methyl donor that supports normal liver methylation and healthy lipid metabolism within the liver. Betaine supports the normal conversion of homocysteine to methionine and helps prevent the accumulation of fat in the liver by supporting normal phosphatidylcholine synthesis — a critical phospholipid for healthy hepatocyte membrane function.*
Beet root also provides naturally occurring nitrates that support normal nitric oxide production and healthy circulation, and a broad spectrum of antioxidant pigments (betalains) that contribute to the formula's overall antioxidant profile.*
A precision botanical approach to liver support
Hepa Cleanse™ is built around a specific and complementary set of hepatic mechanisms: direct hepatocyte protection via milk thistle silymarin, bile stimulation and cholesterol metabolism support via dandelion and artichoke, hepatic detoxification and lymphatic support via burdock, and liver methylation and lipid metabolism support via beet root betaine. Each botanical was selected by Dr. Marchese for a defined and distinct role — and together they address liver health more comprehensively than a single-botanical formula.*
At a glance — what this formula supports
- Normal liver cell integrity and hepatoprotective antioxidant defence via Milk Thistle 80% silymarin*
- Normal bile production and healthy cholesterol metabolism via Dandelion & Artichoke*
- Normal hepatic detoxification and lymphatic function via Burdock root*
- Normal liver methylation and healthy hepatic lipid metabolism via Beet root betaine*
- Comprehensive liver and gallbladder wellness as part of a healthy lifestyle*
Quality you can verify
Every batch of Hepa Cleanse™ is manufactured in a GMP-certified facility, 100% vegetarian, non-GMO, and third-party tested for purity and potency. Developed exclusively by Dr. Marchese. All five botanicals standardised to active compounds for verified potency.
60 vegetarian capsules per bottle (30 servings).
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Warnings
WARNING: If you are pregnant or breastfeeding, consult your physician before using this product. If you have a liver condition, gallbladder disease, bile duct obstruction, or are taking medications, consult your healthcare provider before use. Not recommended during active acute hepatitis without healthcare provider supervision.
