SIBO Support Bundle | Dr. Morstein's Four-Stage Protocol — SIBOtic™ + SIBO-MMC™ + SIBO-Rebuild™ + SIBOZyme™ | Priority One
$280.00
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SIBO Support Bundle — The Complete Four-Stage Dr. Morstein SIBO Supplement Protocol: Eradicate, Prevent Recurrence, Repair & Support Digestion
The SIBO Supplements Support Bundle brings together Dr. Mona Morstein ND's complete four-stage SIBO protocol in a single bundle — a comprehensive, sequenced approach to SIBO management developed by one of North America's leading naturopathic SIBO specialists. Each of the four formulas addresses a distinct and essential phase of SIBO treatment and recovery, from initial bacterial eradication through motility restoration, mucosal repair, and digestive enzyme support.*
Note: SIBOZyme™ is included as the standard version (with Betaine HCl). If your healthcare provider has recommended the No HCL version, please purchase SIBOZyme™ (No HCL) separately.
The four-stage protocol
Stage 1: SIBOtic™ — Eradicate
SIBOtic™ is the antimicrobial treatment stage — a high-dose, four-compound botanical formula targeting the bacterial and archaeal overgrowth that defines SIBO. It combines Garlic extract 1% allicin (1,500mg), Berberine HCl 97% from Coptis chinensis (500mg), Caprylic Acid (300mg), and Oregano leaf oil (300mg) — each working through a distinct antimicrobial mechanism.*
These four mechanisms — thiol enzyme alkylation (allicin), DNA intercalation (berberine), membrane disruption (caprylic acid), and membrane potential disruption (oregano oil) — provide broad-spectrum coverage across hydrogen-producing bacteria, methane-producing archaea, and fungal co-colonisers.*
Berberine has been studied in a published randomised controlled trial for equivalence to rifaximin in hydrogen-dominant SIBO eradication. Garlic allicin has documented activity against the methane-producing archaea responsible for methane-dominant SIBO.*
Stage 2: SIBO-MMC™ — Prevent Recurrence
SIBO-MMC™ addresses the single most important mechanism of SIBO recurrence — Migrating Motor Complex (MMC) dysfunction. The MMC is the intestinal housekeeping sweep that clears bacteria from the small intestine between meals; impaired MMC function is the primary reason SIBO recurs after treatment.*
SIBO-MMC™ supports the MMC's primary serotonergic activation pathway via 5-HTP 98% 75mg (the direct serotonin precursor) + P-5-P active B6 15mg (its essential cofactor), combined with Ginger 5% gingerols 200mg (a clinically validated prokinetic that activates motilin and 5-HT4 receptors) and Jujube 2% jujuboside 200mg (enteric nervous system regulatory support).*
Stage 3: SIBO-Rebuild™ — Repair
SIBO-Rebuild™ addresses the mucosal damage and enteric nervous system (ENS) dysfunction that SIBO causes and that, if unaddressed, perpetuates the cycle. It combines L-Glutamine 750mg (primary enterocyte fuel for intestinal barrier repair) and Zinc orotate 10mg (tight junction cofactor) for structural barrier repair, with Lion's Mane whole mushroom 250mg (the only functional mushroom that supports nerve growth factor expression for ENS neuron regeneration) and Acetyl L-Carnitine HCl 750mg (neuronal mitochondrial fuel and acetylcholine precursor for ENS repair).*
The ENS is the neurological control system for the MMC — repairing the ENS with SIBO-Rebuild™ is directly complementary to restoring MMC function with SIBO-MMC™.*
Stage 4: SIBOZyme™ — Support Digestion
SIBOZyme™ addresses the digestive impairment that both accompanies and perpetuates SIBO — ensuring thorough macronutrient digestion prevents undigested food from becoming bacterial substrate. It provides Pancreatin 8X (Amylase 80,000 USP / Lipase 13,200 USP / Protease 80,000 USP), Ox Bile 300mg (replacing SIBO-disrupted bile acid emulsification), Betaine HCl 98% 220mg (gastric acid support for sterilisation and enzyme activation), Lactase / Maltase / Sucrase (replacing SIBO-damaged brush border enzymes), and Tolerase-G® prolyl endopeptidase (DSM) for gluten peptide digestion.*
How to use the protocol
Dr. Morstein's protocol is designed to be used in stages, with SIBOZyme™ used throughout:
Stage 1: Begin with SIBOtic™ for approximately 4 weeks to address the active bacterial/archaeal overgrowth. Use SIBOZyme™ with meals throughout.*
Stage 2: Transition to SIBO-MMC™ (taken between meals to support the fasted MMC) to address motility and prevent recurrence. Continue SIBOZyme™ with meals.*
Stage 3: Add SIBO-Rebuild™ to support intestinal mucosal repair and ENS restoration. Can be used concurrently with Stages 2 and ongoing. Continue SIBOZyme™ with meals.*
Always follow your healthcare provider's personalised protocol guidance. Individual SIBO presentations vary — Dr. Morstein's protocol should be used under naturopathic or integrative medical supervision for best results.
At a glance — what this bundle addresses
- SIBO bacterial/archaeal eradication via four-mechanism botanical antimicrobial protocol (SIBOtic™)*
- MMC motility restoration to prevent recurrence via serotonin pathway support (SIBO-MMC™)*
- Intestinal barrier and ENS repair via mucosal rebuilding nutrients (SIBO-Rebuild™)*
- Comprehensive digestive enzyme and bile acid support throughout (SIBOZyme™)*
- Complete, sequenced four-stage SIBO management system by Dr. Morstein*
Quality you can verify
All four products in the SIBO Support Bundle are manufactured in GMP-certified facilities, third-party tested for purity and potency, and developed exclusively by Dr. Mona Morstein ND. Please refer to individual product labels for full ingredient details and dosing directions.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Warnings
WARNING: Please refer to individual product labels for full warnings and contraindications. SIBOtic™ contains high-dose botanical antimicrobials — not for use in pregnancy or without healthcare provider guidance. SIBOZyme™ contains Ox Bile (not vegetarian/vegan) and Betaine HCl. SIBO-MMC™ contains 5-HTP — consult your healthcare provider if taking MAOIs or SSRIs. This protocol is designed for use under healthcare provider supervision.
The Priority One Difference
Our Quality Promise- 5 stars: 26 (74%)
- 4 stars: 6 (17%)
- 3 stars: 0 (0%)
- 2 stars: 2 (6%)
- 1 star: 1 (3%)
Good product
So far I like it. It hurt my stomach taking it on an empty stomach so I take it with meals now.
My experience started off rough as Sibotic product was out of stock and I was extremely frustrated as I had purchased the 4 Step Sibo solution. I called and spoke with a Customer Service Rep who was very professional (forgot her name) and she did what she could to help me understand the situation. What was impressive is she relayed my message of frustration to your company leadership and I quickly got a return call from Lena, stating she may have a solution for me and would do what she could to find away to fulfil my order. I am sincerely grateful and amazed by the level of service and effort several people went through to take care of my need and hope to have found a solution for my challenging health issues and ongoing frustration with finding a treatment that I feel good about. I'm in the process of incorporating this new treatment and wanted to express my appreciation to Lena and all those who have given me new hope.
Didn’t help. I bought this because I have a lot of gas(burping), which drives acid reflux. This did not help at all. I’m not sure if I’m being fair giving it a low rating. But I’m not willing to spend 60+ dollars to give it more time. I didn’t notice any difference in the burping or reflux. I know that this does not say that it will help reflux, But it did not help with the gas and burping either.
It works well without any side effects.
After 4 weeks of un-diagnosed diarrhea, I tried this product. Within a week it was cleared up. I am continuing to take it and have less bloating, gas and discomfort in my intestines.
VENDEN LO QUE OFRECENRECOMENDADOS 100%
My doctor has me on this to help manage SIBO and it has been great
New for me - has positively affected regularity
Symptoms came back, can't find instructions on coughing, etc. regimen. Fodmap difficult w/ other food restrictions. Followed with Probiotics. On 2nd round.
Thank you for taking the time to leave a review for our SIBOtic product. We are sorry to hear that your symptoms have returned and we understand how frustrating this can be. We suggest taking a look at our blog for instructions on how to properly take the SIBO line of products to ensure that your symptoms do not recur. We hope that our products can continue to support your health journey.
Yes! It works for me.
I had Methane based Sibo eight years ago. I have always been careful since then with my diet, but...honestly, the last year or so got off track. My digestive system was so back up, even taking a low fodmap fiber supplement further constipated me. I am small (5'0 and 110 lbs) I found I had to decrease the dose to two pills (instead of three) due to severe stomach/GI tract cramping. BUT!!! After my FIRST DOSE, I had movement! I hadn't had a Bowel Movement in weeks, and within a few hours of my first dose, "ta-da!!!" hallelujah!!!! Ultimately, we all need to find what work for use. SIBO MMC has been my saving grace. I am not where I need to be yet, but I have hope. There is so much impacted in my tract, it will take a while to clean out. I am meeting with a dietician, and we have not necessarily ruled out a SIBO test. (yet to be determined.)
I am so grateful she did research and found SIBO MMC for me, as I would not have heard of it otherwise. I highly recommend this product for anyone who has suffered from (methane) SIBO and still has motility issues.
The functional medicine provider I see said to take this to prepare my guy for an intense pre/probiotic regimen; that this would make the process more gradual and successful.
The functional medicine provider I saw said to take this before starting another intense pre/probiotic. It helped prepare my gut for transformation!
Second round of SIBOtic, hopefully will help get rid of SIBO, just wish the capsules were smaller !
If been on and off sibotic for 3 years now and everyrime I have to go back on I’m amazing that this works! I take it with neem capsules and it is miraculous.
I have a very severe gastrointestinal condition, and I have tried many products. Most don't help, and of those that do, SIBO MMC produces the least side effects. It has helped me lead a more normal life.
This supplements do work. Best treatment for Sibo.
After two rounds of failed antibiotics I found this product and am so glad I did. I am able to eat normally and have zero bloating and pain
I began using SIBOtic a week ago and within a matter of days I began to see an improvement in my digestion. I’ve had absolutely no stomach discomfort or any side effects. Thank you for a great product!
Works well on the leaky gut syndrome. Heals. Repairs.
These supplements have been so helpful after recovering from SIBO. Love them!
Really helps reduce sibo symptoms, very impressed after about 20 days, gut healing at its best.
This product has really helped to improve by digestive health. I have experienced less bloating and discomfort
I'm using SIBO-Rebuild in conjunction with SIBO-MMC, and they seem to help relieve my bloating.
These may be helpful for sibo, ???, but the price has gone up by like 20%. What is wrong with these GREEDY supplement makers. find the ingredients somewhere else. I have had it with these price increases.
I'm suffering for SIBO BAD BREATH for almost 10 years and I thank God I bump on this product. Yes it's pricey but man this is life changer. I received mine Friday afternoon so I took 1 capsule but I vomited and had severe headache at the same time diarrhea that is super smelly. I rehydrate myself and in the morning I ate breakfast and took another capsule. I never had headache but I feel like super hungry even I just ate. It's only my second capsule but I noticed my breath is getting better and I don't feel bloated and I kept pooping with very stinky poop. Then dinner I took 1 again. Another morning I brush my teeth with no smell anymore. I took this together with enzymes but I can say this is the best. Today it's Sunday I took it 1 capsule Three times a day until I can adjust but I'm so happy with the result. I'm looking forward that this SIBO BREATH will be totally gone. Thank You Lord for the wisdom of this person who created this.
I developed SIBO after GI surgery. A very, very expensive 14-day course of Xifaxan did nothing to ease my symptoms. I found this product online by chance, and I decided to try it. I've been taking just one capsule with dinner for a week and my symptoms are already completely gone! I'm even starting to put some weight back on (SIBO made me very underweight), which has been amazing. I am so glad I found this product!