Thyroid Plus™ | Thyroid Glandular 130mg, L-Tyrosine, L-Aspartic Acid, Zinc & B Vitamins for Comprehensive Thyroid Support | 120 Capsules

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Thyroid Plus™ — Thyroid Glandular 130mg with L-Tyrosine, L-Aspartic Acid, Thyroid-Specific B Vitamins & Minerals for Comprehensive Thyroid Support

Thyroid Plus™ is Priority One's comprehensive thyroid support formula — combining a meaningful dose of Thyroid glandular concentrate (130mg) with L-Tyrosine (the primary amino acid precursor to thyroid hormones), L-Aspartic Acid, a high-potency B vitamin complex, and the minerals most critical for normal thyroid hormone synthesis: Zinc, Magnesium, Manganese, and Potassium. Where the pure thyroid glandular products (32.5mg, 65mg, 130mg, 300mg) provide glandular tissue alone, Thyroid Plus™ provides the full nutritional ecosystem that surrounds and supports normal thyroid function.*

Please note: Thyroid Plus™ contains Thyroid glandular and is encapsulated in gelatin — not suitable for vegetarians or vegans.

Serving size is 2 capsules, 60 servings per container (120 capsules).


What's inside and why it matters

Thiamine HCl (Vitamin B1, 30mg, 2,500% DV) — A high-potency B1 dose supporting normal energy metabolism via pyruvate dehydrogenase — the entry point to the Krebs cycle. B1 is particularly relevant to thyroid support because thyroid hormones regulate cellular energy metabolism, and B1 is a primary cofactor for the energy-generating pathways that thyroid hormones control.*

Riboflavin (Vitamin B2, 50mg, 3,846% DV) — A critical FAD/FMN coenzyme cofactor for cellular energy metabolism and thyroid peroxidase (TPO) — the enzyme responsible for the oxidation and organification of iodide in thyroid hormone synthesis. Adequate riboflavin is essential for normal TPO function and normal thyroid hormone production.*

Niacin as Niacin/Niacinamide 50/50 (52mg NE, 325% DV) — A blend of free niacin and non-flushing niacinamide supporting normal NAD+ synthesis — essential for the energy metabolism that thyroid hormones regulate — and normal thyroid gland cellular repair.*

Magnesium as Magnesium Aspartate Oxide (40mg, 10% DV) — A multi-form magnesium blend supporting normal thyroid hormone deiodination — the conversion of T4 to the active T3 form — via its role as a cofactor for deiodinase enzymes, and supporting normal energy metabolism in thyroid-responsive tissues.*

Zinc as Zinc Picolinate Oxide (10mg, 91% DV) — Zinc picolinate in a highly bioavailable form at 91% DV. Zinc is one of the most important trace minerals for normal thyroid hormone synthesis and metabolism. It is required for normal thyroid hormone receptor function (thyroid hormone receptors are zinc finger transcription factors), normal thyroid-stimulating hormone (TSH) production, and normal T4 to T3 conversion via 5'-deiodinase activity.*

Manganese as Manganese Citrate Carbonate (2mg, 87% DV) — Supporting normal antioxidant enzyme function (Mn-SOD) in thyroid tissue — the thyroid generates hydrogen peroxide as part of normal thyroid hormone synthesis, making antioxidant protection of thyroid tissue particularly important.*

Potassium as Potassium Chloride Aspartate (40mg, <1% DV) — Supporting normal electrolyte balance and normal cellular membrane potential in thyroid-responsive tissues.*

Thyroid Glandular Concentrate (130mg per serving) — 130mg of desiccated thyroid glandular concentrate providing tissue-specific factors from thyroid tissue — thyroid peptides, thyroglobulin, thyroid-specific enzymes, and regulatory proteins involved in normal thyroid hormone synthesis and cellular thyroid function. In the context of Thyroid Plus™, the 130mg glandular dose is combined with the nutritional cofactors required to support its activity — creating a more functionally complete thyroid support formula than the glandular alone.*

L-Aspartic Acid (298mg per serving) — The highest-dosed active ingredient in this formula. L-Aspartic Acid is an amino acid that supports normal mitochondrial energy metabolism (via the malate-aspartate shuttle), normal pituitary function, and normal TSH (thyroid-stimulating hormone) production. Aspartic acid is concentrated in pituitary tissue and supports normal pituitary-thyroid axis regulation — the upstream control system that drives normal thyroid hormone production.*

L-Tyrosine (250mg per serving) — The second highest-dosed active ingredient and arguably the most targeted thyroid-specific nutrient in this formula. L-Tyrosine is the essential amino acid building block for thyroid hormone synthesis. Both T4 (thyroxine — four iodine atoms attached to two tyrosine residues) and T3 (triiodothyronine — three iodine atoms attached to two tyrosine residues) are synthesised by the thyroid gland through iodination of tyrosine residues within thyroglobulin. Without adequate L-Tyrosine, thyroid hormone synthesis is impaired regardless of iodine availability.*

L-Tyrosine also supports normal catecholamine synthesis (dopamine, norepinephrine, epinephrine) — relevant because thyroid hormones regulate catecholamine sensitivity throughout the body.*


Thyroid Plus™ vs pure thyroid glandular — when to use each

Priority One's pure thyroid glandular products (32.5mg, 65mg, 130mg, 300mg) provide isolated thyroid tissue concentrate — appropriate for practitioners who want precise glandular dosing without additional cofactors. Thyroid Plus™ combines 130mg of thyroid glandular with the full nutritional support system for normal thyroid function: the amino acid precursor to thyroid hormones (L-Tyrosine), the pituitary support amino acid (L-Aspartic Acid), the enzymatic cofactor minerals (Zinc, Magnesium, Manganese), and the B vitamin energy metabolism cofactors. It is the more comprehensive daily thyroid support formula.*


At a glance — what this formula supports

  • Normal thyroid hormone synthesis via L-Tyrosine (thyroid hormone amino acid precursor)*
  • Normal thyroid gland tissue support via Thyroid glandular 130mg*
  • Normal pituitary-thyroid axis function and TSH regulation via L-Aspartic Acid*
  • Normal T4 to T3 conversion via Zinc (deiodinase cofactor) & Magnesium*
  • Normal thyroid peroxidase activity via Riboflavin B2 (TPO cofactor)*
  • Normal energy metabolism in thyroid-responsive tissues via high-potency B vitamin complex*

Quality you can verify

Every batch of Thyroid Plus™ is manufactured in a GMP-certified facility and third-party tested for purity and potency. Thyroid glandular sourced from New Zealand grass-fed cattle. Gelatin capsule — not suitable for vegetarians or vegans.

120 capsules per bottle (60 servings).

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Warnings

WARNING: If you are pregnant or breastfeeding, consult your physician before using this product. Thyroid Plus™ contains Thyroid glandular — use under the supervision of a qualified healthcare provider with appropriate thyroid function monitoring. Do not use as a substitute for prescribed thyroid hormone replacement therapy without healthcare provider guidance. Not suitable for vegetarians or vegans.

The Priority One Difference

The Priority One Difference

Our Quality Promise
  • 5 stars: 21 (91%)
  • 4 stars: 1 (4%)
  • 3 stars: 1 (4%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
A
Andrea S (Edmonton, AB, CA)
120 Capsules
Thyroid Support

Great product. Always feel my best when on it

A
Anonymous (Seattle, WA, US)
60 Capsules
Na

Na

A
Anonymous (Portland, OR, US)
120 Capsules
Great product

Great product. Keeps my thyroid balanced.
Been using for years.

A
Anonymous (Burnaby, BC, CA)
60 Capsules
Great product!

I've been using this product for years...because it works.

A
Anonymous (Miami, FL, US)
60 Capsules
Product Helps a lot and the shop is reliable and

Product Helps a lot and the shop is reliable and fast

M
Mkeilhofer (San Jose, CA, US)
120 Capsules
Works great

These helped me a lot.

M
Margo (New Westminster, BC, CA)
Pure and trusted

The only one that works for me recommended by my naturopath. Pure ingredients that I trust.

T
Theresa (Denver, CO, US)
120 Capsules
Great product

I've been taking this supplement for quite some time and it keeps my thyroid levels normal. I like that it's a natural product rather than something cooked up in a lab.

J
Jean R (Warren, PA, US)
120 Capsules
Thyroid Plus and Thyroid 130

I have been using Thyroid Plus and Thyroid 130 for over 15 years because I had low thyroid. My thyroid blood work has been normal with no need for medication. I am so grateful!

K
Katie Rozinski (Las Vegas, NV, US)
120 Capsules

Helped me regulate my thyroid that I no longer take medication- per Dr. supplements and diet help!

R
Rae Perry (Charlotte, NC, US)
120 Capsules
Successfully gotten off meds

I’ve been able to successfully get off NP thyroid after 10 years with this supplement! Amazing. I feel great. Thank you!

c
corina compton (Bullhead City, AZ, US)
60 Capsules
Great brand

My doctor put me on this and this stuff is amazing so far labs are looking amazing.. Ty

J
Jamie (Las Vegas, NV, US)
Only one that helps!

My naturopath recommended this one to me again after the first thyroid supplement I was on wasn’t doing the job.

I have ongoing issues with my thyroid and have used this one before which helped balance out my numbers. So now I am on it again and it’s the only thing that really makes me feel better.

J
Janet Gilliland (Estacada, OR, US)
120 Capsules
?

How would I know what the Thyroid Plus is doing for me? I'm not a doctor . Unless I get a fasting blood draw and have an in-depth analysis done, there is no way to tell how effective the supplement is.

N
Nikki (Regina, SK, CA)
120 Capsules

Works well so far

M
Mary Key (Montrose, CO, US)
120 Capsules
Thyroid Plus

I've been using this product for most of the last 10 or so years and find that it helps me feel pretty good. I like it better than any of the synthetic thyroid meds out there (which I've used in the past). So please keep it in stock. MK

S
Sally (Clearwater, FL, US)
120 Capsules
Great supplement

This is great stuff! It helps me keep my thyroid balanced and keeps my energy up. I’d highly recommend it.

R
Reid Thiemer (Nanaimo, BC, CA)
120 Capsules

Excellent product

C
Christine Zecca (Kīhei, HI, US)
120 Capsules
The only Thyroid Supplement I use

All I can say is "It works". So pleased I can stop searching.

S
Stephanie Olver (Noxen, PA, US)
120 Capsules
It works!

Helps keep my thyroid regulated. Highly recommend it. S.O.

P
PJ (Vancouver, WA, US)
120 Capsules
great product

Have used it for years on a doctor's recommendation and it has kept me healthy!

P
Paula Peterson (Bayfield, CO, US)
120 Capsules
I love my Thyroid Plus!

I had a prescription from my doctor for a few years, but the prescription was not optimal for my thyroid. My doctor switched me to Priority One's Thyroid Plus and my thyroid tests come back better than when I was on the prescription! Better for my thyroid - better for me!

C
Catherine Bow (Innisfail, AB, CA)
120 Capsules
Thyroid Plus

Have been using Thyroid Plus for the past 8 years with great results! Highly recommend this product & the excellent customer care of Priority One.