Gluten Resolve™ — Tolerase™G Gluten-Specific Enzyme & Comprehensive Digestive Support for Gluten Sensitivity
For those who follow a gluten-free diet but regularly encounter trace gluten exposure — through cross-contamination, restaurant meals, or unlabelled ingredients — standard digestive enzymes are insufficient. Breaking down the immunogenic peptides in gluten requires a specific enzyme: prolyl endopeptidase. Gluten Resolve™ is built around Tolerase™G — the leading gluten-specific enzyme — combined with a comprehensive broad-spectrum digestive enzyme blend, dual probiotics, and parsley leaf for complete digestive support.*
Important note: Gluten Resolve™ is designed to support the digestion of occasional trace gluten exposure — it is not intended to enable the deliberate consumption of gluten by individuals with coeliac disease, and is not a substitute for a gluten-free diet. It is designed for individuals following a gluten-free lifestyle who want additional enzymatic support for accidental or trace exposure.*
Serving size is 3 vegetarian capsules, 30 servings per container (90 capsules). Contains gluten-free maltodextrin.
What's inside and why it matters
Tolerase™G Prolyl Endopeptidase (300mg per serving, from Aspergillus niger)
Tolerase™G is a trademarked prolyl endopeptidase (PEP) enzyme developed by DSM — one of the world's leading enzyme science companies. It is the defining ingredient in this formula and the one that makes it fundamentally different from standard digestive enzyme products.
Gluten is a protein found in wheat, barley, and rye, composed primarily of glutenin and gliadin subunits. The immunogenic peptides in gluten — the ones responsible for triggering adverse responses — are unusually rich in proline amino acids. Human digestive enzymes (proteases) struggle to cleave next to proline residues, meaning these proline-rich peptide sequences survive digestion largely intact and reach the small intestine where they can trigger immune responses.*
Prolyl endopeptidase specifically cleaves peptide bonds adjacent to proline residues — precisely the bonds that human proteases cannot efficiently cleave. Tolerase™G breaks down the proline-rich immunogenic peptides in gluten into smaller, less immunogenically active fragments during gastric digestion, before they reach the small intestine. This is why only a gluten-specific prolyl endopeptidase can address the root enzymatic challenge of gluten digestion.*
At 300mg per serving, Gluten Resolve™ provides a substantial, meaningful dose of Tolerase™G — aligned with the amounts studied in research on this specific enzyme.*
Papain (240mg, 3,000 USP units/mg) — A high-potency proteolytic enzyme from papaya, active across a wide pH range covering both stomach and intestinal environments. Papain provides broad-spectrum protein-digesting activity to complement the gluten-specific action of Tolerase™G, supporting the overall digestion of all dietary proteins.*
Protease from Aspergillus oryzae (105mg, 500,000 HUT/g) — A high-activity fungal protease at 500,000 HUT/g — a very high specific activity — providing targeted intestinal-phase protein digestion alongside Tolerase™G and papain.*
Sucrase from Saccharomyces cerevisiae (105mg, 10,000 Su/g) — Sucrase breaks down sucrose into glucose and fructose, supporting normal carbohydrate digestion and addressing common sucrose malabsorption discomfort.*
Lactase from Aspergillus oryzae (15mg, 100,000 ALU/g) — At 100,000 ALU/g specific activity — an extremely high-potency lactase — this provides meaningful lactose-digesting support despite the lower dose weight. Lactase deficiency is common and often co-occurs with gluten sensitivity.*
Amylase from Aspergillus oryzae (30mg, 25,000 SKB/g) — High-activity fungal amylase providing starch and carbohydrate digestion support, complementing the formula's comprehensive enzyme coverage.*
Lipase from Aspergillus niger, Candida rugosa & Rhizopus oryzae (30mg, 80,000 LU/g) — A multi-source, ultra-high-activity lipase blend at 80,000 LU/g providing comprehensive fat-digesting support for normal absorption of fat-soluble nutrients alongside the broader enzyme profile.*
Cellulase from Trichoderma longibrachiatum (27mg, 20,000 CU/g) — High-activity cellulase supporting the breakdown of plant cell walls for improved nutrient bioavailability from plant foods.*
Lactobacillus acidophilus (375 million CFU at time of agglomeration) — Supporting normal small intestinal flora balance, healthy gut barrier integrity, and a balanced intestinal microbiome alongside the enzyme activity.*
Bifidobacterium bifidum (750 million CFU at time of agglomeration) — The higher-CFU probiotic strain in this formula, supporting large intestinal microbiome balance and healthy immune function. Together, these strains provide dual-compartment probiotic support for the digestive environment.*
Parsley Leaf (Petroselinum crispum, 3mg) — A culinary herb naturally rich in flavonoids, chlorophyll, and vitamins C and K. Included as a complementary digestive support botanical with traditional use for supporting normal digestive comfort and gut wellness.*
What Gluten Resolve™ is — and isn't
Gluten Resolve™ is a specialised enzymatic support formula for individuals following a gluten-free diet who encounter trace gluten exposure. It provides the specific prolyl endopeptidase enzyme — Tolerase™G — that the human digestive system cannot produce in sufficient quantities to break down gluten's immunogenic proline-rich peptides, alongside a comprehensive digestive enzyme blend, probiotics, and botanical support.*
It is not a licence to consume gluten. It is not intended for individuals with coeliac disease as a substitute for dietary compliance. It is a meaningful enzymatic tool for managing the reality that a perfectly gluten-free diet is extremely difficult to maintain in the real world.*
At a glance — what this formula supports
- Targeted breakdown of gluten's immunogenic proline-rich peptides via Tolerase™G*
- Comprehensive protein digestion via papain & high-activity fungal protease*
- Normal digestion of all macronutrients via full enzyme spectrum*
- Lactose digestion support via ultra-high-activity lactase*
- Healthy gut microbiome balance via dual Lactobacillus & Bifidobacterium strains*
- Digestive comfort during trace gluten exposure as part of a gluten-free lifestyle*
Quality you can verify
Every batch of Gluten Resolve™ is manufactured in a GMP-certified facility, 100% vegetarian, certified gluten-free formula, non-GMO, and third-party tested for purity and potency. Features Tolerase™G — a trademark of DSM.
90 vegetarian capsules per bottle (30 servings).
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Warnings
WARNING: If you are pregnant or breastfeeding, consult your physician before using this product. This product is not intended for use by individuals with coeliac disease as a substitute for a gluten-free diet. If you have coeliac disease or a serious gluten-related disorder, consult your healthcare provider before use. If you have a gastrointestinal condition or are taking medications, consult your healthcare provider before use.
